Amplification of Porcine SRY Gene for Sex Determination
نویسندگان
چکیده
منابع مشابه
Sry: the master switch in mammalian sex determination.
SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex determination. Recent studies in mice reveal that the major role of SRY is to achieve sufficient expression of the related gene Sox9, in order to induce Sertoli cell differentiation, which in turn drives testis formation. Here, we discuss the cascade of events triggered by SRY and the mechanisms that reinforce the differ...
متن کاملارزیابی آزمون تکثیر هم دمای وابسته به حلقه جهت تعیین جنسیت جنین در انسان
Background and purpose: In humans, SRY (sex-determining region of the Y chromosome) is the major gene for the sex determination which is found in normal XY males and rarely in XX males, and it is absent from normal XX females and from many XY females. There are several methods which can indicate a male genotype by amplification of SRY gene. The aim of this study was identification of the SRY ge...
متن کاملInteractions between SRY and SOX genes in mammalian sex determination.
The SRY gene on the mammalian Y chromosome undoubtedly acts to determine testis, but it is still quite unclear how. It was originally supposed that SRY acts directly to activate other genes in the testis-determining pathway. This paper presents an alternative hypothesis that SRY functions indirectly, by interacting with related genes SOX3 (from which SRY evolved) and SOX9 (which appears to be i...
متن کاملA new method for sex determination based on detection of SRY, STS and amelogenin gene regions with simultaneous amplification of their homologous sequences by a multiplex PCR.
We have developed a new method for sex determination based on simultaneous detection of the SRY (sex-determining region Y), STS (steroid sulfatase) and amelogenin (AMELX and AMELY) gene regions and their homologous sequences. The sex of 246 blood samples was correctly determined by this method. An AMELY-deleted male sample, which would have been erroneously considered female based solely on ana...
متن کاملExpression of Sry, the mouse sex determining gene.
In the mouse, Sry is expressed by germ cells in the adult testis and by somatic cells in the genital ridge. Transcripts in the former exist as circular RNA molecules of 1.23 kb, which are unlikely to be efficiently translated. We have used RNase protection to map the extent of the less abundant Sry transcript in the developing gonad. We demonstrate that it is a linear mRNA derived from a single...
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ژورنال
عنوان ژورنال: Asian-Australasian Journal of Animal Sciences
سال: 2009
ISSN: 1011-2367,1976-5517
DOI: 10.5713/ajas.2009.90034